Israeli generics giant Teva Pharmaceutical Industries (NYSE: TEVA) has entered into an exclusive partnership with South Korea’s Celltrion (Kosdaq: 068270) to commercialize two of Celltrion’s monoclonal antibody (MAb) biosimilar candidates in the USA and Canada.
CT-P10 is a proposed MAb biosimilar to Rituxan (rituximab), from Roche (ROG: SIX) and Biogen (Nasdaq: BIIB), which is used to treat patients with non-Hodgkin’s lymphoma (NHL), chronic lymphocytic leukemia (CLL), rheumatoid arthritis (RA), Wegener’s granulomatosis and microscopic polyangiitis (MPA).
CT-P6 is a proposed MAb biosimilar to Herceptin (trastuzumab), also from Roche, which is used for the treatment of HER2-overexpressing breast cancer and for the treatment of HER2-overexpressing metastatic gastric or gastroesophageal junction adenocarcinoma. Combined annual net sales for Rituxan and Herceptin are around $6.5 billion in the USA and Canada.
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