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BioAge Lab

A clinical-stage biopharma company developing therapeutic product candidates for metabolic diseases, such as obesity, by targeting the biology of human aging.

The company has nominated a member of this class, the orally available, small-molecule brain-penetrant NLRP3 inhibitor BGE-102, as a development candidate. The structurally novel drug has potential best-in-class features, including high potency and high brain penetration, an important attribute for a compound that could be used for treatment of neuroinflammation linked to conditions such as obesity. IND-enabling experiments for BGE-102 are being conducted as of Q1 2025, and Phase I SAD data are anticipated by the end of 2025.

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