Time to sink or swim: CinCor seeks Phase III test for novel heart med

29 November 2022

A Phase II miss for CinCor Pharma (Nasdaq: CINC) has sent the firm’s stock falling precipitously. Shares are now changing hands for around $14, 45% lower than last week.

The drop comes after top-line results were announced following the completion of the HALO trial of baxdrostat, a novel small molecule which blocks the aldosterone synthase enzyme.

CinCor is testing the candidate as an option for people with uncontrolled hypertension taking up to two blood pressure medications at the maximally tolerated doses.

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