Zepbound bests Wegovy in head-to-head weight loss trial
The battle between the two front runners in the vast weight loss treatment market took a turn today, when US pharma major Eli Lilly (NYSE: LLY) released top-line results from the SURMOUNT-5 Phase IIIb open-label randomized clinical trial.
The study demonstrated that Lilly’s Zepbound (tirzepatide) provided a 47% greater relative weight loss compared to Novo Nordisk’s (NOV: N) Wegovy (semaglutide).
On average, Zepbound led to a superior weight loss of 20.2% compared to 13.7% with Wegovy. At 72 weeks, Zepbound beat Wegovy on both the primary endpoint and all five key secondary endpoints in this trial of adults living with obesity or overweight with at least one weight-related medical problem and without diabetes.
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