An international coalition of leading rheumatologists has announced the launch of the new DINORA (Definitive Intervention in New-Onset Rheumatoid Arthritis) trial that will investigate infliximab (Schering-Plough and Centocor's Remicade) in the treatment of very early inflammatory arthritis to determine whether or not it can prevent the development of destructive rheumatoid arthritis. DINORA was launched at the European League Against Rheumatism annual meeting in Lisbon, Portugal, June 19, and will be partially funded by S-P and Centocor.
"We anticipate very positive results from the ASPIRE trial (Active Controlled Study of Patients Receiving Infliximab for Treatment of Rheumatoid Arthritis of Early Onset) which looked at the combination of infliximab plus methotrexate in patients with early RA," said Peter Lipsky, scientific director of the National Institute of Arthritis and Musculoskeletal and Skin Diseases, part of the USA's National Institutes of Health. "DINORA will examine various combinations of infliximab and methotrexate in patients at an even earlier stage of RA - some of whom are only a few weeks into the disease. We are now exploring the possibility of a cure for RA," he added.
This article is accessible to registered users, to continue reading please register for free. A free trial will give you access to exclusive features, interviews, round-ups and commentary from the sharpest minds in the pharmaceutical and biotechnology space for a week. If you are already a registered user please login. If your trial has come to an end, you can subscribe here.
Login to your accountTry before you buy
7 day trial access
Become a subscriber
Or £77 per month
The Pharma Letter is an extremely useful and valuable Life Sciences service that brings together a daily update on performance people and products. It’s part of the key information for keeping me informed
Chairman, Sanofi Aventis UK
Copyright © The Pharma Letter 2024 | Headless Content Management with Blaze