Tezspire Phase III results show sustained effect in chronic rhinosinusitis with nasal polyps
Amgen (Nasdaq: AMGN) and AstraZeneca (LSE: AZN) have announced full results from the Phase III, registrational WAYPOINT trial showing that Tezspire (tezepelumab-ekko) significantly reduced nasal polyp severity, the need for surgery and systemic corticosteroid use in patients with chronic rhinosinusitis with nasal polyps (CRSwNP [nasal polyps]).
Treatment with Tezspire significantly reduced nasal polyp severity measured by the co-primary endpoints of nasal polyp score (NPS) and nasal congestion score (NCS) at week 52 compared to placebo.
Improvements in NPS were observed as early as week four and, in NCS, as early as week two—the first post-treatment assessments, respectively—and were sustained through week 52.
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