Licensing agreement deal value for innovative T-cell receptor (TCR) immunotherapy drugs surged in 2024, with European biopharmaceutical companies reporting a 325% surge ($921 million) from 2023 to 2024 year-to-date (YTD), compared to a 90.5% rise ($256 million) in the USA, according to pharma analytics company GlobalData.
GlobalData pointed out that TCR-based immunotherapies harness their unique ability to recognize both antigens on cancer cells and intracellular antigens presented by the major histocompatibility complex, setting them apart from CAR-T cells, which primarily targets surface proteins.
“This advantage enables TCR immunotherapies to address a broader range of tumor antigens, including those that are challenging for other treatments to detect,” commented Ophelia Chan, business fundamentals senior analyst at GlobalData
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