Talks with Enhertu makers end without agreement, says the NICE

20 November 2024

The UK’s health technology assessor the Institute for Health and Clinical Excellence (NICE) says that talks with the makers of Enhertu have ended without agreement, meaning guidance that does not recommend Enhertu for advanced breast cancer will remain unchanged.

Enhertu (trastuzumab deruxtecan), the antibody-drug conjugate (ADC) will remain off of the NHS as developers AstraZeneca (LSE: AZN) and Daiichi Sankyo (TYO: 4568) "did not put forward a cost-effective price that would have enabled us to recommend Enhertu as value for money for the taxpayer," the NICE said.

“We are extremely disappointed that talks to reach a price agreement that would have made advanced breast cancer drug Enhertu available to around 1,000 women in England and Wales have not been successful,” commented NICE chief executive Dr Samantha Roberts

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