Sino-American deal in immuno-oncology

2 August 2024

Dallas, Texas-based Instil Bio (Nasdaq: TIL) and China’s ImmuneOnco Biopharmaceuticals (1541: HK) have announced a license and collaboration agreement.

The deal will see Instil in-license ex-China development and commercial rights to ImmueOnco’s proprietary PD-L1xVEGF bispecific antibody, IMM2510, as well as its next-generation anti-CTLA-4 antibody, IMM27M.

IMM2510 is a potentially best-in-class bispecific antibody consisting of an anti-PD-L1 antibody fused to a vascular endothelial growth factor (VEGF) receptor trap which binds VEGF.

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