Roches licenses novel DLL3 ADC from Innovent

2 January 2025

China’s Innovent Biologics (HKEX: 01801) today announced a collaboration and exclusive license agreement with Swiss pharma giant Roche (ROG: SIX) to advance the development of IBI3009, a novel DLL3-targeted antibody drug conjugate (ADC) candidate.

This adds to the growing list of big pharma licensing and M&A deals in the attractive area of ADCs, but Innovent’s shares dipped 3% to HK$35.50 on the news.

IBI3009 has already obtained investigational new drug (IND) approvals in Australia, China, and the USA, with the first patient for the Phase I study dosed in December 2024. This collaboration aims to bring innovative treatment options to patients with advanced small cell lung cancer.

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