Positive top-line Phase IIa results for Metsera’s obesity drugMET-097i

7 January 2025

Metsera today announced positive data from a 12-week Phase IIa clinical trial of MET-097i, its potential once-monthly, ultra-long acting, subcutaneously injectable, fully-biased, GLP-1 receptor agonist (RA).

New York USA-based Metsera, a company accelerating the next generation of medicines for obesity and metabolic diseases, announced its launch in April 2024, along with $290 million financing.

The randomized, double blind, placebo-controlled, Phase IIa trial enrolled 120 participants with obesity and overweight who did not have type 2 diabetes. MET-097i was tested in five cohorts of 24 participants (20 active drug, 4 placebo).

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