Positive Phase III trial results for ensitrelvir
Japan’s Shionogi (TYO: 4507) yesterday delivered a late-breaking scientific oral presentation at the Conference of Retroviruses and Opportunistic Infections (CROI) 2025 on its ensitrelvir.
This included new data from its global, double-blind, randomized, placebo-controlled Phase III study, Stopping COVID-19 pRogression with early Protease InhibitOr treatment – Post-Exposure Prophylaxis (SCORPIO-PEP) assessing ensitrelviras oral post-exposure prophylaxis.
Shionogi stated that SCORPIO-PEP is the first and only Phase III study of a COVID-19 oral antiviral as a post-exposure prophylaxis to meet the primary endpoint of preventing COVID-19.*
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