Zambon trial upset by pandemic but results are encouraging

19 July 2023
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Zambon, a privately-owned Italian pharmaceutical company, has announced results from the Phase III PROMIS-I and PROMIS-II studies.

The studies examined the use of colistimethate sodium (CMS) powder for a nebulizer solution, delivered by the I-neb Adaptive Aerosol Delivery (AAD) system.

The approach is known as CMS I-neb, and is being developed for use in people with non-cystic fibrosis bronchiectasis (NCFB) and certain lung infections, with the goal of reducing pulmonary exacerbations.

There are no approved inhaled treatments for this patient population.

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