Zafgen's obesity treatment beloranib demonstrates weight loss in Phase II results

18 November 2013

Privately-owned US biopharmaceutical company Zafgen has announced final efficacy and safety data from its Phase II study of beloranib, a selective inhibitor of methionine aminopeptidase 2 (MetAP2), for obesity.

These findings, presented at Obesity Week 2013 on Friday, demonstrated significant weight loss and improvements in cardiometabolic risk markers in 147 obese individuals over 12 weeks of treatment, the largest and longest trial to date for the beloranib program.

An alternative to surgery

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