The oral JAK1/2 inhibitor CYT387 has emerged as Canada-based YM BioSciences’ (TSX: YM) lead development project, having been acquired through last year’s takeover of the Australian biotech company Cytopia, say analysts at Edison Investment Research.
Three significant deals involving competing JAK inhibitors have been struck in the past 18 months or so - showing big pharma’s growing interest in the JAK inhibitor mechanism - and CYT387 is one of the most advanced unpartnered projects in development. It is also the only one to have shown a significant response rate in anemia in myelofibrosis, which could help to differentiate it from competitors.
ASCO presentations underscore potential
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