ViiV says Phase III maraviroc study shows inferior efficacy to emtricitabine/tenofovir

22 July 2014

ViiV Healthcare – a joint venture with UK pharma major GlaxoSmithKline (LSE: GSK) as the main partner with Pfizer (NYSE: PFE) and Shionogi (TYO: 4507) – has shown that a regimen of maraviroc dosed once daily combined with darunavir/ritonavir showed inferior efficacy when compared with emtricitabine/tenofovir with darunavir/ritonavir.

The company presented these findings at the 20th International AIDS Congress in Melbourne, showing the results of a Phase III study on antiretroviral-naive subjects. The research, however, did not meet the -10% non-inferiority endpoint.

Maraviroc no better than emtricitabine and tenofovir in anti-virals

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