Germany’s Institute for Quality and Efficiency in Health Care (IQWiG), which had already assessed a dossier on dolutegravir in spring 2014, has now examined in another dossier of the fixed-dose combination of dolutegravir/abacavir/lamivudine, marketed by ViiV Healthcare as Triumeq, to assess whether the drug combination also offers an added benefit over the appropriate comparator therapy. ViiV Healthcare is a joint venture majority owned by GlaxoSmithKline (LSE: GSK), and partnered with Pfizer (NYSE: PFE) and Shionogi (TYO: 4507).
According to the findings, there is an indication that adults who have not been treated for their HIV infection have considerable added benefit from treatment with the new fixed-dose combination. However, an added benefit versus the appropriate comparator therapy is not proven for adults with antiretroviral pre-treatment and for adolescents with and without pre-treatment, because suitable study data are lacking.
No evaluable data for adolescents and pre-treated adults
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