Vertex updates on suzetrigine (VX-548) in acute and neuropathic pain
US biotech Vertex Pharmaceuticals’ (Nasdaq: VRTX) shares gained ground in early trading today after the company signaled progress in the development of its experimental non-opioid pain treatment.
Vertex announced important advancements across its suzetrigine pain program, which has the potential to be the first new class of medicine for acute and neuropathic pain in more than two decades. Suzetrigine is an oral selective NaV1.8 pain signal inhibitor (formerly known as VX-548).
Following the positive Phase III results in acute pain announced in January 2024, the US Food and Drug Administration (FDA) has granted a rolling New Drug Application (NDA) submission for suzetrigine in moderate-to-severe acute pain.
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