US pharma majors join forces on Factor XIa inhibitors
US healthcare giant Johnson & Johnson’s (NYSE: JNJ) Janssen unit has entered a new worldwide collaboration with Bristol-Myers Squibb (NYSE: BMY) on a program to develop and commercialize Factor XIa (FXIa) inhibitors, including BMS-986177, for the prevention and treatment of major thrombotic conditions.
Under the agreement, Janssen Pharmaceuticals and Bristol-Myers will advance BMS-986177 into Phase II clinical trials and establish a broad development program across multiple therapeutic indications.
Janssen will pay Bristol-Myers Squibb an undisclosed upfront sum along with potential development and regulatory milestone payments. The companies will share development costs and commercial profits and losses. Additional terms of the agreement were not disclosed.
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