Unfazed by past failures, Lilly offers up to $1.7 billion for novel Alzheimer's tech

12 December 2018

Bucking the trend of drugmakers departing the Alzheimer’s space, Eli Lilly (NYSE:LLY) has announced it will buy into AC Immune’s (Nasdaq: ACIU) program, based around the less mainstream "tau hypothesis," which posits misformed tangles of protein are behind the degenerative disorder.

Many pharma companies have dropped research in Alzheimer’s after years of failure, leading to a dwindling end-stage pipeline for candidates.

Others, such as the UK’s TauRx Therapeutics, believe a change in the research paradigm, away from the central “amyloid hypothesis,” is required.

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