In a reversal of its earlier draft decision, the UK’s health technology assessor has provided final draft guidance recommending Eisai’s (TYO 4523) Kisplyx (lenvatinib), in combination with everolimus, as an option for treating kidney cancer.
The combination therapy is recommended as an option for treating certain advanced renal cell carcinoma patients who have had one previous treatment with vascular endothelial growth factor (VEGF)-targeted therapy.
Tokyo-based Eisai must provide Kisplyx at a discount agreed during a patient access scheme, reducing the current list price of £1,437 ($1,929) for 30 capsules.
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