Trial hold slows type 1 diabetes work at vTv Therapeutics

30 July 2024

Shares in North Carolina, USA-based vTv Therapeutics (Nasdaq: VTVT) have fallen over a quarter after the firm announced a clinical hold on its diabetes program.

The company is running a Phase III trial of cadisegliatin, an oral, liver-selective glucokinase activator, for people with type 1 diabetes.

The US regulator has stopped work on the CATT1 trial after the detection of a “chromatographic signal” that mass spectrometry could not resolve.

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