Trial disappointment for lupus candidate anifrolumab

31 August 2018

Cambridge, UK-based AstraZeneca (LSE: AZN) and its biologics arm MedImmune have announced a Phase III trial failure for systemic lupus erythematosus (SLE) candidate anifrolumab.

The result comes as a severe disappointment for lupus patients, after the candidate passed its Phase II test in 2015 with flying colors.

The late-stage trial did not meet the primary endpoint of a statistically-significant reduction in disease activity in patients with SLE, as measured by a commonly-used scale.

This article is accessible to registered users, to continue reading please register for free. A free trial will give you access to exclusive features, interviews, round-ups and commentary from the sharpest minds in the pharmaceutical and biotechnology space for a week. If you are already a registered user please login. If your trial has come to an end, you can subscribe here.

Try before you buy

Free

7 day trial access

Take a Free Trial

All the news that moves the needle in pharma and biotech
Exclusive features, podcasts, interviews, data analyses and commentary from our global network of life sciences reporters.
Receive The Pharma Letter daily news bulletin, free forever.

Become a subscriber

£820

Or £77 per month

Subscribe Now

Unfettered access to industry-leading news, commentary and analysis in pharma and biotech.
Updates from clinical trials, conferences, M&A, licensing, financing, regulation, patents & legal, executive appointments, commercial strategy and financial results.
Daily roundup of key events in pharma and biotech.
Monthly in-depth briefings on Boardroom appointments and M&A news.
Choose from a cost-effective annual package or a flexible monthly subscription

The Pharma Letter is an extremely useful and valuable Life Sciences service that brings together a daily update on performance people and products. It’s part of the key information for keeping me informed

Chairman, Sanofi Aventis UK