Teva buys rights to MODAG's neurodegenerative disease candidate

27 October 2021

Israel’s Teva Pharmaceutical Industries (NYSE: TEVA) and German drug developer MODAG GmbH have signed an exclusive worldwide licensing and development agreement for MODAG's lead compound anle138b and a related compound, sery433.

Anle138b targets pathological alpha-synuclein oligomers and is being evaluated in patients with neurodegenerative diseases for potential disease modification. Under the terms of the agreement and pending regulatory clearance, Teva will receive an exclusive global license to develop, manufacture and commercialize anle138b and sery433.

The companies will jointly develop the compounds for the multiple system atrophy (MSA) and Parkinson’s disease (PD) indications based on early-stage clinical studies, and consider exploring additional indications based on clinical outcomes. Financial terms of the collaboration were not disclosed.

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