Tempero Bio raises $70 million to advance addiction pipeline

25 March 2025

US biotech Tempero Bio has raised $70 million in a series B financing and brought in a new chief medical officer as it pushes ahead with clinical development of its lead candidate, TMP-301, for substance use disorders.

The funding round was led by 8VC, with Aditum Bio, Khosla Ventures and others joining in. The capital will support two Phase II studies of TMP-301, targeting alcohol use disorder and cocaine use disorder, as well as Phase III-enabling activities and additional preclinical research.

John Wagner has stepped into the role of chief medical officer, taking over from Bruce Imbert. Dr Wagner previously held the same position at digital biomarker firm Koneksa Health and had a five-year tenure at Takeda (TYO: 4502), where he served as senior vice president of translational research and early clinical development.

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