Takeda Pharmaceutical (TSE: 4502) and its co-development partner Zinfandel Pharmaceutical have announced that the Phase III TOMMORROW trial of pioglitazone has been brought to a premature end.
The Japanese drugmaker paid $9 million in 2011 for rights to Zinfandel’s technology to help develop the candidate, with the potential for up to $78 million more in milestones.
Now, following years of development, the Phase III trial has shown inadequate treatment effect in delaying the onset of mild cognitive impairment due to Alzheimer’s disease.
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