Takeda out-licenses Japan rights to relugolix in women's health indications

31 May 2018
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Takeda Pharmaceutical (TYO: 4502) has entered into a licensing agreement to grant fellow Japanese drugmaker ASKA Pharmaceutical exclusive commercialization right for uterine fibroids and exclusive development and commercialization rights for endometriosis for Japan to maximize the product value of Takeda-owned relugolix (development code: TAK-385).

Takeda’s shares edged up 1.55% to 4,452 yen following the announcement this morning.

Relugolix is being developed as a gonadotropin-releasing receptor antagonist to be taken orally, once daily against uterine fibroids, endometriosis and prostate cancer.

Positive top-line results were reported from a Phase III trial of relugolix for the treatment of pain associated with uterine fibroids last November. Relugolix met the primary endpoint of Takeda's trial, with 57.6% of women achieving marked improvement in pain symptoms compared to 3.1% of women receiving placebo.

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