Small molecule drugs are carving a significant niche in lung cancer treatment, an area in which AstraZeneca (LSE: AZN) achieved a landmark approval from the US Food and Drug Administration (FDA) following the results of the Phase III AURA trial.
The 2015 approval of Tagrisso (osimertinib) marked a significant advancement in the treatment of metastatic EGFR T790M mutation-positive non-small cell lung cancer (NSCLC).
Tagrisso is projected to be a pivotal contributor to AstraZeneca’s portfolio, with anticipated sales expected to surpass $7 billion and a 48% market share of small molecules in lung cancer treatment by 2029, according to GlobalData.
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