Supply issues cause Takeda to drop manufacturing of Natpar/Natpara

5 October 2022
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Japan’s largest drugmaker Takeda (TYO: 4502) says that it will discontinue manufacturing its injectable parathyroid hormone Natpar/Natpara globally at the end of 2024 due to unresolved supply issues that are specific to the product.

As a result, Takeda will not re-commercialize the horm one in the USA, where it uses the brand name Natpara, and will discontinue manufacturing Natpar globally. Natpar/Natpara came to Takeda via its $62 billion acquisition of UK-based Shire.

Until the end of 2024, Takeda’s key priority is to maintain treatment continuity for patients who are currently receiving Natpar/Natpara, subject to available supply. This includes those enrolled in the US Special Use Program and all patients receiving Natpar in Europe and other regions around the world. Beyond 2024, Takeda intends to supply available doses until inventory is depleted or expired.

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