Success for Takeda in trial testing subcutaneous version of vedolizumab
Japan’s Takeda Pharmaceutical (TTO: 4502) has unveiled positive top-line results from the VISIBLE 1 clinical trial looking into a new subcutaneous version of its top-selling anti-inflammatory vedolizumab, currently marketed in intravenous form as Entyvio.
The trial is investigating the new formulation as a maintenance therapy for adult patients with moderately to severely active ulcerative colitis (UC) who are responding well to Entyvio.
Takeda says the trial met its primary endpoint, with a statistically-significant proportion of patients receiving vedolizumab SC beginning at week 6 and every two weeks following achieving clinical remission at week 52, compared to placebo.
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