Seladelpar study results raise prospects for first-in-class therapy

20 May 2024
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Gilead Sciences (Nasdaq: GILD) has announced positive interim results from the ongoing ASSURE study of seladelpar.

The investigational PPAR delta agonist is being developed to reduce pruritus in people living with primary biliary cholangitis (PBC), an indication for which there are currently no approved medicines.

70% of people receiving seladelpar 10mg achieved the clinically meaningful composite endpoint and 37% achieved ALP normalization at 12 months.

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