The runaway success of Adcetris (brentuximab vedotin) ensured the future of Seattle Genetics (Nasdaq: SGEN) as an antibody-drug conjugate (ADC) specialist, but chief executive Clay Siegall has bigger ideas about the breadth of focus for the growing company.
The story starts, however, with Adcetris, a product which took in $307 million for the firm last year, compared to $266 million the year before, plus tens of millions in ex-US royalties via a longstanding commercialization deal with Japan’s Takeda Pharmaceutical (TYO: 4502).
Asked about his firm's focus on ADCs, and the strategic rationale behind this approach, Mr Siegall says: "For years there have been some very strong antibodies which, on their own are powerful and can treat patients.”
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