Santen and TRACON link up for TRC105 in ophthalmology

4 March 2014

USA-based TRACON Pharmaceuticals and Japan’s Santen Pharmaceutical (TYO: 4536) have entered into an exclusive agreement for the development and global commercialization of the US firm’s anti-endoglin antibodies, including TRC105, in ophthalmology.

Preclinical and clinical data from TRACON's ongoing development of TRC105 in combination with anti-VEGF products in oncology indicate inhibiting both the endoglin and VEGF pathways has the potential to show advantages over inhibiting VEGF alone in the treatment of conditions such as wet age-related macular degeneration (wet AMD).

$10 million upfront to TRACON

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