Sanofi's Adlyxin slightly safer than Novo Nordisk blockbuster but effectiveness questions remain, report says

22 August 2016

A new comparison claims that Adlyxin (lixisenatide), a drug from French pharma major Sanofi (Euronext: SAN) which gained US Food and Drug Administration (FDA) approval last month for type 2 diabetes, is safer than a top-selling treatment marketed by Novo Nordisk (NOV: N).

Advera Health Analytics has compared Adlyxin, a once-daily mealtime glucagon-like peptide-1 receptor agonist (GLP-1 RA) injection indicated as an adjunct to diet and exercise, with thje Danish company’s Victoza (liraglutide) and Byetta (exenatide), sold by Anglo-Swedish pharma major AstraZeneca (LSE: AZN).

The report states: “Adlyxin showed a slightly safer profile compared to Victoza based on a lower serious adverse events rate in head-to-head trials, and no associated thyroid cancer risk which has been tied to Victoza in rare cases.

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