Sanofi-Aventis in-licenses Oxford BioTherapeutics antibody for the treatment of solid cancers

25 January 2011

Privately-held, UK-based Oxford BioTherapeutics (OBT) said this morning that French drug major Sanofi-Aventis (Euronext: SAN) has acquired an exclusive worldwide license to one of OBT’s internal preclinical antibody programs.

Sanofi-Aventis intends to use the licensed antibody, which is directed against a novel, proprietary target identified by OBT, to develop, manufacture and commercialize antibody drug conjugate (ADC) products for the treatment of cancer. ADC products comprise toxins attached to antibodies which form effective therapeutic products that attack tumor cells in a highly targeted manner.

Under the terms of the deal, Sanofi-Aventis agreed to pay OBT an undisclosed upfront cash payment. The UK firm is also eligible for development and regulatory milestone payments on the program, royalties on the worldwide products sales and will receive additional performance milestones.

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Chairman, Sanofi Aventis UK