French pharma major Sanofi (Euronext: SAN) has signed a global collaboration with privately-held US firm MyoKardia to discover and develop first-of-its-kind targeted therapeutics for heritable heart diseases known as cardiomyopathies, the most common forms of heart muscle disease.
The collaboration builds upon MyoKardia's pioneering science, which hopes to correct the disruptive effects that disease mutations have on heart muscle contraction.Representing one of the largest R&D commitments to genetic forms of cardiomyopathy, the accord encompasses three MyoKardia programs. Two of these programs are focused on hypertrophic cardiomyopathy (HCM) and the other is focused on dilated cardiomyopathy (DCM).
Involves up to $200 million in equity investments, milestones
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