Sage scraps dalzanemdor after disappointing trial results

21 November 2024

Sage Therapeutics (Nasdaq: SAGE) will down tools on its dalzanemdor program, after the Phase II DIMENSION trial missed both primary and secondary endpoints.

The news caps a challenging year for the Massachusetts-based biotech, which has seen its share price fall almost 80% since January.

Sage has been developing dalzanemdor as an option for cognitive impairment in Huntington’s disease, but will now stop all ongoing trials, including the PURVIEW open-label safety study.

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