Safety signal stops Phase III trial of German Merck's big MS hope

13 April 2023

News that the US regulator is to pause enrollment in a key trial of evobrutinib has hit shares of developer Merck KGaA (MRK: DE).

The partial hold comes after lab tests suggest the potential for liver damage caused by the drug.

The German company is trialing the oral Bruton’s tyrosine kinase (BTK) blocker as an option for relapsing multiple sclerosis (RMS).

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