Safety concern deals blow to Merck & Co's HIV program

22 November 2021

Merck & Co (NYSE: MRK) has hit the pause button on a Phase II trial of its investigational HIV combo, MK-8507 and islatravir.

MK-8507 is a non-nucleoside reverse transcriptase inhibitor, whereas islatravir is a nucleoside reverse transcriptase translocation blocker.

The combination is being tested in the IMAGINE-DR clinical trial, as a once-weekly oral treatment for HIV-1 infection.

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