Roundup of upcoming cancer drug trials to be presented at ASCO

20 May 2011

A number of leading pharmaceutical companies – include Pfizer, Bayer, Roche and AstraZeneca - have pre-released data regarding investigation cancer drugs that are due to be presented at the forthcoming 47th Annual American Society of Clinical Oncology (ASCO) meeting in Chicago, which takes place June 3-7, 2011.

Axitinib in kidney cancer

Global drugs behemoth Pfizer (NYSE: PFE) announced data from the pivotal Phase III AXIS 1032 trial, showing that in patients with previously treated advanced renal cell carcinoma (RCC), axitinib significantly extended progression-free survival (PFS) [HR=0.665, 95% CI; P<0.0001], with a median PFS of 6.7 months (95%CI, 6.3-8.6), compared with 4.7 months (4.6-5.6) for those treated with sorafenib, a standard of care for this patient population. PFS was significantly longer in axitinib-treated patients compared to those treated with sorafenib, regardless of prior therapy with Sutent (sunitinib malate) or cytokines.

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