RNAi approach gathers steam with more positive data for Alnylam

28 September 2018

East Coast, USA-based Alnylam Pharmaceuticals (Nasdaq: ALNY) has released positive top-line results from an interim analysis of the ENVISION Phase III Study of givosiran.

Givosiran is an investigational RNAi therapeutic under development for the rare disease acute hepatic porphyria (AHP).

Results of the interim analysis show that givosiran treatment was associated with a statistically-significant reduction in urinary ALA levels, compared with placebo.

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