Results reward investment in Farxiga as heart drug

30 March 2020

A new sub-analysis of the landmark Phase III DAPA-HF trial has showed positive efficacy for Farxiga (dapagliflozin) in treating cardiovascular conditions.

At the same time, UK-based AstraZeneca (LSE: AZN) announced it would halt the DAPA-CKD Phase III trial for Farxiga in chronic kidney disease due to “overwhelming efficacy.”

In DAPA-HF, the SGLT2 inhibitor was shown to have reduced the incidence of the primary composite endpoint of heart failure (HF) worsening or cardiovascular (CV) death, compared to placebo.

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