Regulatory submissions for crinecerfont on the way after Phase III win
Californian biotech Neurocrine Biosciences (Nasdaq: NBIX) has announced positive top-line data from the Phase III CAHTALYST study of crinecerfont.
The company is testing the small molecule as an option for people with classic congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency.
Crinecerfont is a selective corticotropin-releasing factor type 1 receptor (CRF1) antagonist. A group of genetic conditions leading to an enzyme deficiency, CAH can result in salt wasting, dehydration, and even death.
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