Proteostasis and Roche ink development and licensing deal

17 December 2018

Shares in Boston-based Proteostasis Therapeutics (Nasdaq: PTI) are up nearly a fifth in pre-market trading, after the firm announced a global, exclusive license agreement with Roche (ROG: SIX) subsidiary Genentech.

Proteostasis is working on cystic fibrosis (CF) therapies, as well as treatments for other diseases caused by dysfunctional protein processing.

Roche is paying for rights to potential therapeutic small molecule modulators of an undisclosed target within the proteostasis network. The network consists of more than 1,000 proteins organized into pathways that can be regulated or targeted by drugs.

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