Proteostasis and Astellas link on up to $1.2 billion R&D deal

5 November 2014
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Japanese drug major Astellas Pharma (TYO: 4503) has entered into a collaboration with US drug developer Proteostasis Therapeutics to develop new drugs for an unspecified genetic disease and, potentially, other unnamed disease types.

The worldwide collaboration aims to research and develop therapeutic candidates that modulate the Unfolded Protein Response (UPR) through the use of Proteostasis’ proprietary “Disease Relevant Translation” (DRT) and “Proteostasis Network” platform. Proteostasis Therapeutics will receive an initial upfront payment from Astellas, along with a securities investment.

$400 million research funding and milestone payments

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