Positive results with Taiho's TAS-102 in Asian patients with refractory metastatic colorectal cancer

4 April 2016

Japan’s Taiho Pharmaceutical, a subsidiary of Otsuka (TYO: 4578), has released positive results from its Phase III TERRA study on its oral combination anticancer drug TAS-102 (Japan and US trade name Lonsurf (trifluridine and tipiracil) in Asian (China, South Korea and Thailand) patients with refractory metastatic colorectal cancer (mCRC).

The TERRA study met its primary endpoint of demonstrating improvement in overall survival (OS) in patients with refractory mCRC whose disease had progressed after approved standard therapies. In this study, TAS-102 appeared to be generally well tolerated and its toxicities were consistent with what was previously reported.

More detailed results from this study will be presented at a future international academic conference.

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