US clinical stage biotech RenovoRx (Nasdaq: RNXT) saw its shares leap 30% to $2.90 in pre-market activity, after it released positive interim Phase III data showing an eight-month improvement in progression-free survival (PFS) for patients on RenovoGem (intra-arterial administration of gemcitabine) in locally advanced pancreatic cancer.
The interim data was featured as a late-breaking oral presentation at the 2023 ESMO World Congress on Gastrointestinal Cancer.
The interim analysis demonstrated an eight-month median PFS benefit, 15 versus seven months, in delaying the progression of cancer for patients receiving treatment with RenovoGem versus standard-of-care. PFS is the measure of the length of time from study randomization to either death or progression of disease.
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