Positive data support Linzess to treat symptoms of IBS

19 June 2019

Ironwood Pharmaceuticals (Nasdaq: IRWD) and Allergan (NYSE: AGN) have announced positive top-line data from a Phase IIIb trial evaluating Linzess (linaclotide).

The firms have been evaluating the therapy, a guanylate cyclase-C (GC-C) agonist, in treating multiple abdominal symptoms in adults with irritable bowel syndrome with constipation (IBS-C).

The trial met its primary multi-component endpoint, showing that Linzess improved the overall abdominal symptoms of bloating, pain and discomfort in people with IBS-C, compared to placebo.

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