Positive data on Incruse Ellipta added to Relvar/Breo Ellipta in COPD

11 June 2014

UK pharma giant GlaxoSmithKline (LSE:GSK) and US partner Theravance (Nasdaq: THRX) have released positive results from two Phase III studies evaluating product efficacy in the treatment of chronic obstructive pulmonary disease (COPD).

These showed that patients with COPD who received the anticholinergic, Incruse Ellipta (umeclidinium (UMEC) 62.5mcg), or umeclidinium 125mcg (an unlicensed dose) in addition to Relvar/Breo Ellipta (fluticasone furoate/vilanterol, “FF/VI”), an inhaled corticosteroid / long-acting beta2-agonist combination, achieved an additional improvement in lung function (FEV1) compared to patients receiving FF/VI plus placebo.

The studies showed that for the primary endpoint of trough FEV1 at Day 85, the addition of UMEC 62.5mcg or UMEC 125mcg to FF/VI 100/25mcg resulted in a statistically-significant improvement in lung function when compared with FF/VI 100/25mcg plus placebo in patients with COPD

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