Phase III win for tolebrutinib in progressive multiple sclerosis
Sanofi (Euronext: SAN) has announced encouraging results from its Phase III HERCULES trial of tolebrutinib in people with non-relapsing secondary progressive multiple sclerosis (nrSPMS).
The study, presented at the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) 2024 conference in Copenhagen, showed that tolebrutinib delayed disability progression by 31% compared to placebo.
The trial met its primary endpoint, with results indicating that tolebrutinib delayed the time to onset of six-month confirmed disability progression.
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